How would you manage a patient with synchronous locally advanced rectal adenocarcinoma (T3N2) and a large T2N0 adenocarcinoma of mid and distal esophagus?
Answer from: Radiation Oncologist at Academic Institution
A tough situation no doubt. Def need an MDT agreement with medical oncology and surgery. The patient should be evaluated for surgical (especially esophageal resectability). I am going to try to be creative here : I would vote 5x5 to rectal mass then get on mFOLFOX6 based chemo per C...
Answer from: Medical Oncologist at Academic Institution
It's tempting to try to squeeze chemoradiotherapy when we have 2 tumor areas but it will be too complex for likely marginal advantage.Few things to keep in mind:
We make sure genomics are done and nothing interesting.
Rectal seems more advanced than esophageal. So tailoring therapy for recta...