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Topics:
Head and Neck Cancers • Radiation Oncology
How would you manage recurrent laryngeal cancer after previous larynx xrt if surgical salvage not an option?
Surgical salvage is indicated but not possible in all cases due to comorbidities or patient preference.
Would you re-irradiate and how?
Would you consider SBRT?
Answer from: Radiation Oncologist at Academic Institution
Re-RT for recurrent laryngeal cancer when surgery is not an option was first proposed by CC Wang (IJROBP 1993;26:783-5). He reported reasonable local control rates and stated, at the conclusion of “Radiation Therapy Results†in his paper, that “s...
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Answer from: Radiation Oncologist at Community Practice
I agree with the excellent answers above. To my knowledge, the MIRI data is the only data to directly compare SBRT and IMRT-based re-irradiation to date. All the caveats of retrospective multi-institution data apply. We tried to adjust for potential biases using two methods. After all of this, the t...
Answer from: Radiation Oncologist at Community Practice
I would be very reluctant for retaliation with SBRT as published data shows very high risk of late effects in survivorshttps://www.ncbi.nlm.nih.gov/pubmed/27302512