How would you treat a patient with ER/PR positive breast cancer with a single site of bone metastasis?

Is your approach different for oligometastatic versus oligoprogressive disease? If there is concurrent locally advanced disease, would you treat simultaneously?

Answer from: Medical Oncologist at Academic Institution

I would still treat with hormone therapy and a CDK 4/6 inhibitor. Not clear if the question refers to denovo disease or not. I generally do not treat asymptomatic bone mets with radiation, as there are late effects in patients who have a relatively long life expectancy and no data to sug...

Comments

Medical Oncologist at Private Practice and Digital Health
Endocrine therapy is key, a CDK 4/6 inhibitor migh...

Medical Oncologist at University of Washington
Strongly support the idea of a biopsy here, as som...

Medical Oncologist at SSM Cancer Care
Thanks for answering It s de novo in a young pati...

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How would you treat a patient with ER/PR positive breast cancer with a single site of bone metastasis?

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