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Hematologic Malignancies • Radiation Oncology
How would you treat a Stage I DLBCL invading the mandible?
Would you consider ISRT after 3 cycles of RCHOP, omit radiation and proceed to surgery after 6 cycles of RCHOP, or do something else?
Answer from: Radiation Oncologist at Academic Institution
If a patient had an early-stage DLBCL of the oropharynx (e.g., tonsil) with minimal mandibular invasion, who was otherwise low risk by the IPI, then I think 3 cycles of R-CHOP followed by consolidation RT (30 Gy) would be quite reasonable. If the disease was bulky or if there was significant bone in...
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