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Topics:
Internal Medicine • Thrombocytopenia • Hematology • Benign Hematology • Heparin-Induced Thrombocytopenia
In a patient with a history of HIT, how would you reintroduce Heparin?
Is it only done when heparin is used in an emergency?
Answer from: at Community Practice
When patients with even remote histories of HIT are re-exposed to heparin, there is a very high risk of heparin-PF4 antibody seroconversion (Warkentin and Anderson, PMID 27114458). I have seen two patients who suffered a fatal relapse of HIT (e.g., case one in Kodityal et al., PMID 12890149). Bivali...
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