In which circumstances would you offer adjuvant brachytherapy to a surgically staged patient with endometrial cancer if they have received prior pelvic external beam radiation therapy for a non-gynecologic pelvic tumor?  

Assuming that adjuvant treatment is clearly indicated based on pathology findings, I would likely offer it, with some caveats. Ideally, the previous RT would have been delivered on an adjuvant basis with a dose of 50 Gy or less to the vaginal cuff area. Rather than the typical 700 cGy x 3 fractions,...