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Topics:
Radiation Oncology • General Radiation Oncology
Is ATM a contraindication to radiation therapy?
Published data show a mixed review of late toxicity with adjuvant radiation. What are guiding principles we should use as more patients are getting genetic testing?
https://www.ncbi.nlm.nih.gov/pubmed/11849780
https://www.ncbi.nlm.nih.gov/pubmed/11710885
https://www.ncbi.nlm.nih.gov/pubmed/17517479
https://www.ncbi.nlm.nih.gov/pubmed/14643952
https://www.ncbi.nlm.nih.gov/pubmed/16338099
Answer from: Radiation Oncologist at Community Practice
The data is limited with some concern about increased late efffects including fibrosis and increased risk of contralateral breast cancer caused by RT. I have not used this as absolute contraindication but discussed pros and cons with few patients I have treated and taken all measures to reduce contr...
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