Is it safe to start immunotherapy concurrently with radiation to a bone metastases?

In a patient being treated with a palliative course of radiation for a bony metastasis from lung cancer is it safe to start immunotherapy for POD or would it be preferable to wait until radiation is completed?

Answer from: Radiation Oncologist at Community Practice

Retrospective data for palliative RT and immunotherapy doesn’t suggest increased complications with concurrent use

Comments

Radiation Oncologist at UPMC Hillman Cancer Center
Per Bang et al.:https://www.redjournal.org/article...

Radiation Oncologist at Penn State Milton S Hershey Medical Center
We had good data presented at ASTRO 2018 meeting l...

Answer from: Radiation Oncologist at Community Practice

Great question! This depends on the unique clinical situation with respect to dose, fractionation, and field size. Radiation therapy and immunotherapy in partnership may have the capability of delivering a therapeutic effect exceeding the sum of its parts. The possible relationship has now been...

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Is it safe to start immunotherapy concurrently with radiation to a bone metastases?

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