Is there a role for radiation therapy after chemotherapy for localized anaplastic large cell lymphoma?
If so, should involved site radiation thearpy (ISRT) or involved field radiation therapy (IFRT) be used for the radiation therapy treatment fields? Would the current convention of 30.6 Gy at 1.8 Gy per fraction be an appropriate dose?
Answer from: Radiation Oncologist at Academic Institution
Hard to answer this question as posed. ALCL when localized is primarily confined to skin. Treatment of choice in this circumstance is RT alone, generally 40 gy in conventional fractions. ALCL not primarily in the skin is a systemic disease best rx'd with chemo, rarely localized. For the la...