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Radiation Oncology • Gastrointestinal Cancers
Is there any data comparing neoadjuvant pancreatic SBRT vs standard fractionation in terms of its ability to convert unresectable tumors to resectable tumors?
What percentage of unresectable T4N0 pancreatic body adenocarcinomas with celiac axis involvement and no response to 6c chemo, will convert to resectable with 33 Gray in 5 fractions?
Answer from: Radiation Oncologist at Academic Institution
Essentially zero%... this patient should be referred to a center that is giving ablative doses. (100Gy BED) or a surgeon that will do a celiac axis resection (Appelby). Alternatively, you should be honest and say low dose SBRT and 50.4Gy /28# have very little to offer him. The LAP-07 trial clea...
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