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Breast Cancer • Medical Oncology
Is there any evidence to treat the primary breast tumor with local therapy after a radiographic CR with systemic therapy for stage IV disease?
Young woman with Her2 positive disease involving her right breast, regional lymph nodes, and liver had a CR on PET after therapy with THP and now plans for maintenance HP. Breast MRI showed no evidence of disease after treatment. Any evidence for local treatment to the primary with surgery or radiation?
Answer from: Medical Oncologist at Academic Institution
Resection of the primary breast cancer in setting of stage IV is the question in a number of prospective randomized trials and the answer we have to date there is no overall survival advantage, except in the very small number of patients with a solitary bone mets. However, we know HER2 positive wome...
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