Is there any PFT criteria that you use in guiding decision making to offer transbronchial lung cryobiopsy to patients with interstitial lung disease?  

We really don't have any specific PFT criteria to identify the need for cryobiopsy, but apply the same guidelines to determine the need for open lung biopsy in the decision-making process. Even with the risk of bleeding, cryobiopsy is safe. Unless someone is at high risk for ventilator dependence, ...