Is there specific data on using luspatercept for sickle beta+ thalassemia with transfusion-dependent anemia?  

There is no data currently on the use of luspatercept in any condition other than beta thalassemia, including HbE-beta thalassemia. It has been studied in the beta thalassemia phenotype, both transfusion-dependent and non-transfusion-dependent (adult data published, pediatric trial underway), b...