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Gynecologic Cancers • Medical Oncology
Now that there are three FDA-approved PARP inhibitors for use in ovarian cancer (niraparib, rucaparib, olaparib), how do you decide which one to use?
Answer from: Medical Oncologist at Academic Institution
One, niraparib is only approved for maintenance after treatment of platinum sensitive recurrence. Olaparib and rucaparib are approved for treating active, measurable disease. Olaparib for germline BRCA mutation carriers after 3 prior therapies, rucaparib for treating patients with germline or somati...
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Answer from: at Community Practice
In Brazil public health PARP inhibitors for use in ovarian cancer (niraparib, rucaparib, olaparib) is not available is public hospitals.
The olaparib and rucaparibe were used only in clinical trials.
Olaparib was used in SOLO 1, SOLO 2 and SOLO 3 trials and Rucaparibe was used in Ariel 4 trial.
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