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Regarding CVST, what protocol of heparin dosing do you regularly use and does it change depending on clot burden/ICH status?
Is there any evidence supporting the use of heparin boluses?
Answer from: at Academic Institution
There is very limited randomized evidence for the use of anticoagulation in any form for CVST. We often rely on extrapolations from data on the acute management of DVT in the leg and pulmonary embolus. We are mainly limited to cohort studies and small RCTs. Recent trials in this area include the TO-...
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Answer from: at Community Practice
I agree that data on this topic is sparse. In more stable patients, the current AHA guidelines recommend LMWH over heparin gtt (see: https://www.ahajournals.org/doi/10.1161/STR.0000000000000456#:~:text=Previous%20American%20Heart%20Association%2FAmerican,the%20context%20of%20transient%20risk).
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