Should a short trial of androgen therapy be used in patients with primary adrenal insufficiency suffering from persistent fatigue and hypoactive sexual desire despite sufficient glucocorticoid and mineralocorticoid replacement?  

Considering that adrenal glands are an important source of androgens in women, this approach, especially in symptomatic patients, seems reasonable. I usually use DHEA supplements starting at 25 mg daily and then adjust the dose based on the DHEAS and testosterone levels. Most patients require 12.5 t...