Should patients with asymptomatic GH deficiency be treated with GH replacement therapy if they have prior known severe CAD?   

Yes, GHRT should be discussed with GHD adults independently from symptoms. There is no evidence that GHRT increases the risk of CAD, and in fact, it may be beneficial due to the lowering of total and LDL cholesterol (this is a theoretical benefit, as I am not aware of any study that showed that GHRT...