Please select the option that best describes you:
Should we be aiming for normalization of both late-night salivary cortisol and 24hr urinary free cortisol levels when monitoring response to Cushing's disease treatment?
Answer from: at Community Practice
Ideally, yes, both should be normal. 24 hour UFC may increase but still be within the normal range so normal salivary cortisol provides additional reassurance.
Sign in or Register to read more
Answer from: at Community Practice
I usually follow UFC, but there is some data that in patients with Cushing disease treated with pasireotide there was a greater improvements in systolic/diastolic blood pressure and weight in patients with both normal late night salivary cortisol and UFC compared with only normal UFC (see: Newell-Pr...