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Radiation Oncology • Genitourinary Cancers
To what dose do you treat the seminal vesicles in intermediate and high risk prostate cancer?
Do you treat to full dose or a lower dose with a cone down to the prostate PTV? Is there any data to support a particular dose?
Answer from: Radiation Oncologist at Academic Institution
For men with unfavorable intermediate or high risk prostate cancer and T1c-2 disease, treatment of the SV's is recommended (following what you would do for local control if you had a RP - i.e. complete removal of the SV's) to a total dose of at least 70.2 Gy but rectum permitting (i.e. Rec...
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Answer from: Radiation Oncologist at Academic Institution
I have a similar practice to that of @Anthony V. D'Amico. For all unfavorable intermediate and all high risk I take the seminal vesicle to 79.2 Gy (unless the DVH is unacceptable, which is seldom). As already stated, no data I am aware of, just oncologic principles
Jonathan Twar...
Answer from: Radiation Oncologist at Academic Institution
Fully agree with the above. Dr. Kestin et al at Beaumont provide interesting postoperative pathologic support, especially for the intermediate to higher risk patients. While the proximal 2 cm are at most risk from this database, if it's safe to deliver treatment to most or all of the SVs in interme...