Changes in criteria for hyperparathyroid surgery. In the 2022 5th International conference on asymptomatic hyperparathyroidism, the experts have changed surgical consideration based on a 24 hr urine calcium > 400 to > 250 for women and >400 for men. In 2 different UpToDate entries (both updates in 2024), the recommendation for hyperparathyroid surgery is > 400 on one page and in another page > 250 for women and >300 for men.