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Head and Neck Cancers • Radiation Oncology
What do you consider negative or close margins for tonsillar cancers?
Does your postop dose change or use of chemo change if you have close margins?
Answer from: Radiation Oncologist at Academic Institution
To answer your first question about margin for HPV+ (I assume) tonsillar cancers, one would have to go with the definition on clinical trial. Currently the WashU trial as well as RTOG 1221/ECOG 3311 and the ADEPT trial uses the 3mm cutoff. So a free margin is defined as something>/=3mm. Anything ...
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Answer from: Radiation Oncologist at Academic Institution
I won't use chemo for close margins for tonsilar cancers, particularly if it's HPV positive cancer.