Please select the option that best describes you:
Topics:
Radiation Oncology • Genitourinary Cancers
What dose do you prescribe when treating the prostate in patients with low metastatic burden and what are your dose constraints?
The STAMPEDE trial recently published in Lancet used 55 Gy in 20 fractions but did not include dose constraints.
Answer from: Radiation Oncologist at Academic Institution
I follow the STAMPEDE regimen - either 55 Gy in 20 daily fractions or 36 Gy in 6 weekly fractions. One of the imperatives of the STAMPEDE investigators was to not subject men with low volume metastatic prostate cancer to toxicity - and they found these doses of did not, while still signifi...
Comments
Radiation Oncologist at UCLA | VA Greater Los Angeles Healthcare System
I recently queried several NHS consultants about t...
I recently queried several NHS consultants about t...
Radiation Oncologist at Cleveland Clinic
Here are (apparently) the STAMPEDE protocol dose o...
Here are (apparently) the STAMPEDE protocol dose o...
Radiation Oncologist at St. Vincent Hospital
For the 55 Gy/20 fx regimen, the rectal constraint...
For the 55 Gy/20 fx regimen, the rectal constraint...
Radiation Oncologist at National Institutes of Health Clinical Center
The PTV was defined by a 10mm margin (8mm posterio...
The PTV was defined by a 10mm margin (8mm posterio...
Answer from: Radiation Oncologist at Academic Institution
We've been debating this issue at our institution, too. STAMPEDE also used a 6 Gy x6 delivered one fraction per week regimen. As these are patients likely to live a long time, even if not cured, then the goal in treating the prostate should be to achieve durable local control, while at the same...
Answer from: Radiation Oncologist at Community Practice
Converting to U.S.-style 5 fraction prostate SBRT, would anyone give 7.25 Gy per fraction x 5 fractions for 36.25 Gy, or use a different dose? Treating once weekly, twice weekly, or thrice weekly?
60 Gy in 20 fractions.
60 Gy in 20 fractions, as well.