What factors do you consider when selecting dose/fractionation for whole brain radiotherapy?

In which situations would you consider 37.5 Gy / 15 fx or 20 Gy / 5 fx over 30 Gy / 10 fx?

Answer from: Radiation Oncologist at Academic Institution

I assume this question is for brain metastases patients who are not eligible for hippocampal avoidance WBRT (ineligible criteria including but not limited to - mets 5 mm within either hippocampus, germ cell/small cell/lymphoma, leptomeningeal disease, etc.) - my default WBRT dose fractionation is 30...

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In my experience too, standard diagnostic MRIs are...

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What factors do you consider when selecting dose/fractionation for whole brain radiotherapy?

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