What IHC stains do you routinely use for identifying invasive squamous cell carcinomas?  

In the skin, special stains are generally not needed for the vast majority of SCC. In poorly differentiated tumors or spindle cell tumors, cytokeratin stains or p63 are beneficial (and other stains to exclude other diagnoses). Also, for some SCC, S100-keratin double stain may be helpful in identifyi...