What is optimal therapy for a 5 year delayed recurrence of uterine cancer, rendered NED by solitary pulmonary metastasis resection?
And if the tumor is MSI-H, does that alter your thoughts?
Answer from: at Community Practice
I favor “pseudoadjuvant” therapy with carboplatin + paclitaxel chemotherapy for 6 cycles. I make this recommendation in the absence of strong data to suggest an improvement in outcome with chemotherapy over observation vs. hormonal therapy. The optimal therapy for this patient with ...
Comments
Medical Oncologist at Northwest Georgia Onc Center PC Thank you very much for this detailed answer!
at The Ottawa Hospital Excellent, thoughtful answer and recommendation.
Medical Oncologist at Advocate Health Care Thank you for this!
Medical Oncologist at NYU Winthrop Hospital I would just add that for the CALOR Trial the bene...
Over the years, I have had several patients like this and after pulmonary resection, have just followed them without further therapy and to date no recurrence.
Not much data is available. Consideration of adjuvant therapy, in this case, depends on a number of factors. In a very elderly and frail patient, I would agree with Dr. @William T. Creasman and manage expectantly without any active treatment. In others, I would check ER/PR status and if positive, wo...
Comments
at Legacy Health System Great recommendation. Always best to first conside...
at ProMedica Toledo Hospital Great informative and well considered responses.
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Thank you very much for this detailed answer!
Excellent, thoughtful answer and recommendation.
Thank you for this!
I would just add that for the CALOR Trial the bene...