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Breast Cancer • Radiation Oncology
What is the most accurate method to determine initial tumor size prior to neoadjuvant chemotherapy and mastectomy?
Do you look at pretreatment breast MRI or post surgical assessment of the tumor bed/treatment effect? How would you resolve discrepancies between the two (MRI suggests initial T3 disease but path shows 2 cm treatment effect)?
Answer from: Radiation Oncologist at Community Practice
The pattern of regression after neoadjuvant chemo is not always consistent. It could be concentric where the tumor regresses uniformally in all direction and thus the final tumor is unifocal and much smaller than imaging (percentage regression suggests the degree of response to chemo). Or it could b...
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