What is the optimal sequencing for SBRT boosts in prostate cancer?
Should the boost be delivered before or after EXBRT? What is the ideal delay (if any) between the two?
Answer from: Radiation Oncologist at Community Practice
I prefer to follow the schedule used on the PROMETHEUS trial (prospective, phase 2) and have had good results. Wegener et al., PMID 38302321 This protocol delivered an upfront 2-fraction SBRT boost with each fraction given 1 week apart. The EBRT component (46 Gy in 23 fractions) was then d...