What is the role of adrenalectomy in managing isolated recurrence of stage IIIc melanoma, occurring 2 years after the original diagnosis, in a patient who declined adjuvant therapy?  

Is the adrenal gland the only site of recurrence? Also, is the recurrence unilateral or bilateral? Unilateral adrenalectomy will not lead to permanent adrenal insufficiency, but bilateral adrenalectomy will (the patient will end up needing maintenance steroids permanently and need to have an endocri...