What is the role of consolidative radiotherapy in a Stage IV triple hit lymphoma with partial response above and below diaphragm s/p 8 cycles of RCHOP?
Specifically, would you consolidate initially bulky sites or allow patient to proceed to next line systemic therapy / transplant?
Answer from: Radiation Oncologist at Academic Institution
The role of consolidation RT in advanced (stage III-IV) DLBCL and HGBCL continues to evolve. Presently, I often recommend consolidation RT in a few clinical circumstances including:
Bulky disease (sites > ~7 cm)
Disease in particularly sensitive locations (e.g., base of skull or epidural spac...