What is your approach to managing sicca symptoms in patients not responding or not tolerating conservative measures, pilocarpine, and cevimeline?
Answer from: at Community Practice
Try lower doses of pilocarpine with just 1/4 tablet at a time. Very slowly go up on the dose as tolerated. The patient's job is to find the maximum tolerated dose. I recommend this pill splitter:
Mix capsule of cevimeline in water, just drink a tiny bit at a time tid and go up on dose as tolera...
Comments
at Michigan State Univeristy Bethanechol comes in 5, 10, 25, and 50 mg. Dosing ...
at Uniformed Services University of the Health Sciences (USUHS) @John Kolstoe: I greatly appreciate your answer. I...
at Tristate Arthritis & Rheumatology @Donald E. Thomas, Thank you for the helpful infor...
at Michigan State Univeristy ~2016, I was referred a patient with sicca from on...
at University of California, Berkeley and San Francisco Oral medicine colleague and Director of Sjogren's ...
at Uniformed Services University of the Health Sciences (USUHS) Thanks, @Nancy. Helpful, practical advice.
Bethanechol comes in 5, 10, 25, and 50 mg. Dosing ...
@John Kolstoe: I greatly appreciate your answer. I...
@Donald E. Thomas, Thank you for the helpful infor...
~2016, I was referred a patient with sicca from on...
Oral medicine colleague and Director of Sjogren's ...
Thanks, @Nancy. Helpful, practical advice.