What is your approach to the initial treatment of metastatic melanoma patients with NRAS mutations?
How do you treat these patients if they progress after immune checkpoint inhibitors?
Answer from: Medical Oncologist at Academic Institution
The incidence of NRAS mutations in the metastatic setting has been reported in up to 15-20% of patients. There are currently no FDA approved agents specifically for NRAS mutated patients who progress after immunotherapy. Some studies have shown these patients may have bett...