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Breast Cancer • Radiation Oncology
What role, if any, should Ki-67 play in decision making about the role of adjuvant radiotherapy in patients who meet CALGB 9343 entry criteria?
Would a high result give you pause about omission of RT? If yes what level is sufficiently high?
Answer from: Radiation Oncologist at Community Practice
CALGB /PRIME2 study didnt look at Ki67 but did notice grade 3 disease had higher risk of recurrenceThe Canadian study retrospectively did IHC using K167 14% as cut off for Luminal A vs. Luminal B classification and did notice that luminal B had higher IBTR than luminal A, although could not distingu...
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