What RT dose would you use to treat a single site relapse of high risk multiple myeloma?  

Depending on the KPS of the patient, it may be 20 Gy in 5 to 36 Gy in 20. Data (Oertel et al., PMID 30987659) support upwards of over 45 Gy, but that is in the de-novo situation. This is post-treatment/transplant and represents a treatment failure and likely palliation. A 2005 paper on this subject ...