What strategies do you employ to prevent post-intubation hypotension in a profoundly hypoxic patient given a paralytic for intubation?  

There are a few strategies I use. I choose an induction agent such as Etomidate or a ketamine which has minimal hemodynamic effects. If BP is soft to start with, I use IV fluid small bolus, use a vasopressor such as phenylephrine push if needed before sedation.