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What therapy would you recommend for metastatic myxoid liposarcoma in a young patient with anthracycline cardiomyopathy with EF 25% who failed eribulin?
Would you even consider trabectedin in this case given its cardiotoxicity?
Answer from: Medical Oncologist at Academic Institution
I would first make sure that systemic therapy is absolutely necessary, as myxoid liposarcoma can have an indolent course. I have seen patients with disease spanning >20 years. That being said, if systemic therapy is absolutely warranted I would consider trabectedin. Anecdotally, I have used in a ...
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Answer from: Medical Oncologist at Academic Institution
I am going to guess that:1. Patient has doxorubicin cardiomyopathy because she got adjuvant doxorubicin and ifosfamide with initial tumor.2. It was long enough ago that there has been time to develop cardiomyopathy.3. If she was without progression long enough to develop cardiomyop...