What total dose do you use for a close and positive breast cancer margin that cannot be re-excised?
For conventional fractionation, should one increase total dose above 60 Gy for either close or positive margin (invasive or DCIS). What about for accelerated fractionation?
Answer from: Radiation Oncologist at Community Practice
Based on consensus guidelines, there is no such thing as a close margin as HR for recurrence did not change based on margin width. That was the reason for group to conclude that no tumor at inked margin is a negative margin (except for pure DCIS or those who had neoadjuvant chemo).If we give a boost...
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Radiation Oncologist at Kaiser Permanente For a patient with a close margin (< 1mm ), is a b...
Radiation Oncologist at CCare Also wondering this.
Radiation Oncologist at Cleveland Clinic No, I typically don't boost more. With margin defi...
Radiation Oncologist at Lake Huron Medical Center It is very hard to clear residual disease even wit...
Radiation Oncologist at Columbia University Medical Center/ New York Presbyterian / Hudson Valley Hospital @Sushil Beriwal I am having trouble finding the po...
Radiation Oncologist at Varian Medical Systems/Allegheny health network Numbers are not SS as the sample size is very smal...
Radiation Oncologist at Columbia University Medical Center/ New York Presbyterian / Hudson Valley Hospital @Sushil Beriwal Thanks - can you direct me to wher...
Radiation Oncologist at Varian Medical Systems/Allegheny health network Can look at graph and also look at positive margin...
Answer from: Radiation Oncologist at Academic Institution
According to the most recent 2018 ASTRO whole breast fractionation guidelines, in the presence of strong risk factor(s) for local recurrence, such as the single risk factor of positive margins or a combination of risk factors such as young age and close margins, a higher radiation boost dose of 1400...
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Radiation Oncologist at Mon Health Thank you.
Radiation Oncologist at West Virginia University Old data from MCV/VCU (Wazer et al., PMID 9531370)...
Radiation Oncologist at Columbia University Medical Center/ New York Presbyterian / Hudson Valley Hospital @Jondavid Pollock Thanks!
For a patient with a close margin (< 1mm ), is a b...
Also wondering this.
No, I typically don't boost more. With margin defi...
It is very hard to clear residual disease even wit...
@Sushil Beriwal I am having trouble finding the po...
Numbers are not SS as the sample size is very smal...
@Sushil Beriwal Thanks - can you direct me to wher...
Can look at graph and also look at positive margin...