What treatment options would you consider for a metastatic low grade serous ovarian carcinoma that transforms to high grade?
Patient has been treated with carbo/taxol, hormonal therapies, and trametinib to date.
Answer from: at Community Practice
A couple of things to consider for this case, #1 treatment-free interval #2 platinum-free interval #3 bulky disease? #4 recent tumor profiling #5 HRD status? I am assuming that she is motivated to continue treatment. If she had a good and durable response to platinum-doublet in the past then I might...