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When do you choose to give CyBorD over RVd in a newly diagnosed myeloma patient?
Specifically, what regimen would you choose in a patient with new renal failure but not requiring dialysis?
Answer from: Medical Oncologist at Community Practice
I only use VCd when patients are going to be inpatient for a while or the patient is unable to afford an IMiD. For patients with renal insufficiency, where time is of the essence, I recommend Velcade 1.3 mg/m2 SQ days 1,4,8,11 + dex 20 mg days 1,4,8,11 with Revlimid 5-15 mg in newly diagnosed MM. &n...
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Medical Oncologist
I agree with @Craig C. Hofmeister. In patients who need to start a therapy immediately - VCD is attractive since it can be acquired without going through the inevitable delays in the US of getting Lenalidomide. Thus patients with impending / actual severe renal impairment related to myeloma are anot...
Answer from: Medical Oncologist at Academic Institution
agree with Craig's take