Please select the option that best describes you:
Topics:
Psychiatry • Addiction Psychiatry
When do you recommend acamprosate vs naltrexone for medication-assisted therapy in alcohol use disorder?
Answer from: at Academic Institution
I would recommend acamprosate over naltrexone for the following patients:
Patients with moderate to severe hepatic impairment (LFT >5 times the upper normal limits).
Patients whose treatment goal is abstinence and who can stop drinking for 4-5 days before initiation of treatment.
Patients wh...
Sign in or Register to read more
Answer from: at Community Practice
Most addiction doctors use naltrexone as the first-line treatment due to its mixed but overall supportive evidence and easier adherence with once-a-day or once-a-month dosing. Acamprosate, on the other hand, comes in large pills, 2 tablets TID (6 tablets is a lot for some patients), making it challe...