When do you recommend patients get vaccinations with respect to their RT course?
This question has come up most frequently with respect to the flu vaccine recently. Also, frequently this has been asked about the shingles vaccine and pneumovax vaccine year-round.
Answer from: Radiation Oncologist at Academic Institution
I agree with @Sushil Beriwal's reply, and find that some patients are under the impression they are immunocompromised during radiation therapy and thus should avoid vaccines, when in fact the opposite is true. The skepticism behind the science of vaccination also can lead to avoidance, and so I...
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Radiation Oncologist at UCLA | VA Greater Los Angeles Healthcare System I think it's a great idea to make these recommenda...
Answer from: Radiation Oncologist at Community Practice
It is important to get all of the above listed vaccines as scheduled, as the effect of these infections is greater in patients who have reduced immunity because of chemo and/or RT. The new shingles vaccine (shingrix) is not a live attenuated virus, so reduced immunity will not have adverse effects o...
Answer from: Radiation Oncologist at Community Practice
I agree with @Sushil Beriwal and @Neha Vapiwala for most circumstances.However, when irradiating the left lower lobe of the lung or upper abdomen, I try to ensure that patients receive pneumococcal vaccination before treatment begins, due to the potential risk of pneumonia/sepsis from splenic r...
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Radiation Oncologist at Radiation Oncology Associates PA As a follow-up: New preclinical data suggests seas...
Radiation Oncologist at University of Alabama at Birmingham That was an intratumoral injection, not a regular ...
Radiation Oncologist at Radiation Oncology Associates PA Yes. It's clearly different than the discussion of...
Answer from: Medical Oncologist at Academic Institution
Regarding the concern for efficacy of the flu vaccine during periods of immunosuppression, the recently published study by Blanchette et al in JCO showed that being on active chemotherapy for solid tumors did not decrease efficacy of the flu vaccine. For patients undergoing active chemo for hematolo...
Answer from: Radiation Oncologist at Community Practice
Low absolute lymphocyte counts reduce protective immune response to H1N1 vaccine in this pediatric population. Low CD4 T cell count also reduced vaccine efficacy. The Blanchette study is a population-based study of cancer patients evaluating laboratory-confirmed and hospitalization-confirmed influen...
I think it's a great idea to make these recommenda...