When, if ever, would you perform Her2 testing in serous intraepithelial neoplasia of the endometrium?  

It's not known whether HER2 expression or amplification is definitely prognostic for EIN, but I suspect it is and we know it is for stage I uterine serous carcinoma. Seeing HER2 expression in EIN makes me concerned about the possibility of a more aggressive disease. We're currently studying this at ...