When performing adrenal vein sampling, is calculating selectivity index using androstenedione superior to using cortisol alone for determining successful catheterization?
Answer from: at Academic Institution
In our experience, the measurement of androstenedione is particularly beneficial when the AVS is done without Cosyntropin stimulation. While the cortisol gradient may be <2 in such cases, we see a several-fold increase in Androstenedione gradients confirming successful catheterization.