There is no RTOG consensus on boost volume, except to say that it should include the entire mesorectum/presacral region at involved levels + 2 cm in cc directions. According to RTOG 0822, it is recommended that the CTV extends 1 cm into bladder, vagina or prostate. Do you use this parameter for the boost volume? If so, what dose constraint do you use for bladder (as protocol states any volume of bladder > 50 Gy is unacceptable).