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When would you add a vaginal cuff brachy boost to external beam radiation for uterine carcinosarcoma?  

Would you offer EBRT alone or EBRT with vaginal cuff brachytherapy after surgery and chemotherapy for stage III (T3N0) carcinosarcoma of the uterus?

Given propensity for advanced stage carcinosarcoma to recur distantly, what is the utility of adding vaginal cuff brachytherapy to EBRT, if any?

Which pathologic factors would influence this decision? - +/- lymphadenectomy, % myometrial invasion, depth of invasion, uterine serosal involvement, lower uterine segment involvement, cervical stromal invasion, LVI, and/or lymph node involvement.

 



Answer from: Radiation Oncologist at Community Practice
Comments
Radiation Oncologist at UAB Department of Radiation Oncology
Carcinosarcoma of the uterus is considered a high-...
Radiation Oncologist at Varian Medical Systems/Allegheny health network
Unfortunately, there is no prospective study showi...
Radiation Oncologist at Sunnybrook Health Sciences Centre
Agree that there is no prospective data regarding ...
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