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Breast Cancer • Radiation Oncology
Why is it more preferable to perform SLNB after neoadjuvant systemic chemotherapy versus before therapy?
Per NCCN guidelines, SLNB after neoadjuvant chemotherapy is preferred.
Answer from: Radiation Oncologist at Community Practice
Rationale
For clinically negative node, the negative predictive value of SNLN is similar before and after chemo.
Chemo type and Indication is now based on phenotype rather than nodal status.
Doing SNLN after chemo would increase likelihood of node negative disease and this avoid m...
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