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Endocrinology • Bone and Calcium Disorders
Would you add cholecalciferol or ergocalciferol to calcitriol therapy in patients with post operative hypoparathyroidism who have low 25 OH vitamin D levels?
Can 25 OH vitamin D be converted to activated vitamin D outside of PTH mediated mechanisms in some organs?
Answer from: at Academic Institution
Yes, if a person with hypoparathyroidism has a low 25(OH) D level, on calcitriol, I would do several things; first, figure out why it is low; and second, check a serum calcium and phosphorus level. If the calcium is low and the phosphorus is elevated, I would try using cholecalciferol 1000 IU daily ...
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Answer from: at Academic Institution
One explanation for low 25-HYDROXYVITAMIN D is calcitriol induces 24-hydoxlyase increasing its destruction. Yes, always had my patients on vitamin D to treat vitamin D deficiency and gave 50,000 IU of vitamin D2 or D3 once a week for 8 weeks then 50,000 IU every 2 weeks or their equivalent daily.
Y...