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Topics:
Internal Medicine • Rheumatology • Hematology • Benign Hematology • Hemostasis/Thrombosis • TTP
Would you consider caplacizumab in a pregnant patient with iTTP?
Caplacizumab is not FDA approved in pregnant patients, but has been used safely in isolated case reports.
Answer from: Medical Oncologist at Academic Institution
As noted, caplacizumab was not studied in pregnancy (was an exclusion criteria) and is not approved in this setting.With that being said, as noted, caplacizumab use in pregnancy has been described in case reports (1, 2, 3) and in the post-partum setting (4). I would consider the use of caplacizumab ...
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