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Genitourinary Cancers • Medical Oncology
Would you consider neoadjuvant chemotherapy for patients with muscle-invasive bladder cancer who are cisplatin-ineligible?
If so, what chemotherapy regimen would you use? If not, what management options would you generally recommend?
Answer from: Medical Oncologist at Academic Institution
We have level 1 evidence supporting neoadjuvant cisplatin-based chemotherapy followed by cystectomy, there is no evidence supporting non-cisplatin based chemotherapy. Patients unfit for cisplatin should proceed directly to surgery
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