Would you consider perioperative immunotherapy for a patient with locally advanced, resectable gastric cancer but not a candidate for chemotherapy?

On occasion, patients with locally advanced gastric cancer are poor candidates for FLOT-like chemotherapy. Should such patients be taken to surgery upfront or following a course of RT? Would a short course of perioperative immunotherapy be considered in this situation?

Answer from: Medical Oncologist at Academic Institution

Some aspects of the management in this situation are influenced by the surgical candidacy. If this patient is not a candidate for chemotherapy it would be critical to have a multidisciplinary assessment for surgical candidacy. Unfit for chemo but fit for surgery is a relatively uncommon ...

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Medical Oncologist at Walter Reed Natl Military Medcl Center
Thanks for your response! My patient is fairly uni...

Medical Oncologist at Walter Reed Natl Military Medcl Center
PDL1 CPS > 90

Medical Oncologist at Massachusetts General Hospital
I think in the absence of data (there is some data...

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Would you consider perioperative immunotherapy for a patient with locally advanced, resectable gastric cancer but not a candidate for chemotherapy?

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