Would you drop the duration of palbociclib from 1-21 days to 1-14 days if still neutropenic with 75 mg dose in metastatic breast cancer?  

I have seen various "off protocol" solutions that oncologists use, probably with the idea that "some is better than none" (which is often true but hard to know how much benefit in a data free zone). Anecdotally, I've seen: every other week therapy; 3 weeks on and 2 weeks off; and finally 5 days on w...